Characterization of the MeCP2(R168X) Knockin Mouse Model for Rett Syndrome

Rett syndrome, one of the most common causes of mental retardation in females, is caused by mutations in the X chromosomal gene MECP2. Mice deficient for MeCP2 recapitulate some of the symptoms seen in patients with Rett syndrome. It has been shown that reactivation of silent MECP2 alleles can rever...

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Detalles Bibliográficos
Autores principales: Wegener, Eike, Brendel, Cornelia, Fischer, Andre, Hülsmann, Swen, Gärtner, Jutta, Huppke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277341/
https://www.ncbi.nlm.nih.gov/pubmed/25541993
http://dx.doi.org/10.1371/journal.pone.0115444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277341/
https://www.ncbi.nlm.nih.gov/pubmed/25541993
http://dx.doi.org/10.1371/journal.pone.0115444

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