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Characterization of the MeCP2(R168X) Knockin Mouse Model for Rett Syndrome
Rett syndrome, one of the most common causes of mental retardation in females, is caused by mutations in the X chromosomal gene MECP2. Mice deficient for MeCP2 recapitulate some of the symptoms seen in patients with Rett syndrome. It has been shown that reactivation of silent MECP2 alleles can rever...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277341/ https://www.ncbi.nlm.nih.gov/pubmed/25541993 http://dx.doi.org/10.1371/journal.pone.0115444 |