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CREB Targets Define the Gene Expression Signature of Malignancies Having Reduced Levels of the Tumor Suppressor Tristetraprolin

The RNA-binding protein Tristetraprolin (TTP, ZFP36) functions as a tumor suppressor that impairs the development and disables the maintenance of MYC-driven lymphoma. In addition, other human cancers expressed reduced levels of TTP, suggesting that it may function as a tumor suppressor in several ma...

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Detalles Bibliográficos
Autores principales: Fallahi, Mohammad, Amelio, Antonio L., Cleveland, John L., Rounbehler, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277357/
https://www.ncbi.nlm.nih.gov/pubmed/25541715
http://dx.doi.org/10.1371/journal.pone.0115517