SIRT6 Minor Allele Genotype Is Associated with >5-Year Decrease in Lifespan in an Aged Cohort

Aging is a natural process involving complex interplay between environment, metabolism, and genes. Sirtuin genes and their downstream targets have been associated with lifespan in numerous organisms from nematodes to humans. Several target proteins of the sirtuin genes are key sensors and/or effecto...

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Detalles Bibliográficos
Autores principales: TenNapel, Mindi J., Lynch, Charles F., Burns, Trudy L., Wallace, Robert, Smith, Brian J., Button, Anna, Domann, Frederick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277407/
https://www.ncbi.nlm.nih.gov/pubmed/25541994
http://dx.doi.org/10.1371/journal.pone.0115616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277407/
https://www.ncbi.nlm.nih.gov/pubmed/25541994
http://dx.doi.org/10.1371/journal.pone.0115616

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