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Assessment of [(125)I]WYE-230949 as a Novel Histamine H(3) Receptor Radiopharmaceutical

Histamine H(3) receptor therapeutics have been proposed for several diseases such as schizophrenia, attention deficit hyperactivity disorder, Alzheimer's disease and obesity. We set out to evaluate the novel compound, [(125)I]WYE-230949, as a potential radionuclide imaging agent for the histami...

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Detalles Bibliográficos
Autores principales: Lewis, David Y., Champion, Sue, Wyper, David, Dewar, Deborah, Pimlott, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277420/
https://www.ncbi.nlm.nih.gov/pubmed/25542008
http://dx.doi.org/10.1371/journal.pone.0115876