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Investigating Microenvironmental Regulation of Human Chordoma Cell Behaviour

The tumour microenvironment is complex and composed of many different constituents, including matricellular proteins such as connective tissue growth factor (CCN2), and is characterized by gradients in oxygen levels. In various cancers, hypoxia and CCN2 promote stem and progenitor cell properties, a...

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Detalles Bibliográficos
Autores principales: Patel, Priya, Brooks, Courtney, Seneviratne, Ayesh, Hess, David A., Séguin, Cheryle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277432/
https://www.ncbi.nlm.nih.gov/pubmed/25541962
http://dx.doi.org/10.1371/journal.pone.0115909