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Investigating Microenvironmental Regulation of Human Chordoma Cell Behaviour
The tumour microenvironment is complex and composed of many different constituents, including matricellular proteins such as connective tissue growth factor (CCN2), and is characterized by gradients in oxygen levels. In various cancers, hypoxia and CCN2 promote stem and progenitor cell properties, a...
Autores principales: | Patel, Priya, Brooks, Courtney, Seneviratne, Ayesh, Hess, David A., Séguin, Cheryle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277432/ https://www.ncbi.nlm.nih.gov/pubmed/25541962 http://dx.doi.org/10.1371/journal.pone.0115909 |
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