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Selective Lentiviral Gene Delivery to CD133-Expressing Human Glioblastoma Stem Cells
Glioblastoma multiforme (GBM) is a deadly primary brain malignancy. Glioblastoma stem cells (GSC), which have the ability to self-renew and differentiate into tumor lineages, are believed to cause tumor recurrence due to their resistance to current therapies. A subset of GSCs is marked by cell surfa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277468/ https://www.ncbi.nlm.nih.gov/pubmed/25541984 http://dx.doi.org/10.1371/journal.pone.0116114 |