ARAP3 Functions in Hematopoietic Stem Cells

ARAP3 is a GTPase-activating protein (GAP) that inactivates Arf6 and RhoA small GTPases. ARAP3 deficiency in mice causes a sprouting angiogenic defect resulting in embryonic lethality by E11. Mice with an ARAP3 R302,303A mutation (Arap3(KI/KI)) that prevents activation by phosphoinositide-3-kinase (...

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Detalles Bibliográficos
Autores principales: Song, Yiwen, Jiang, Jing, Vermeren, Sonja, Tong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277471/
https://www.ncbi.nlm.nih.gov/pubmed/25542002
http://dx.doi.org/10.1371/journal.pone.0116107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277471/
https://www.ncbi.nlm.nih.gov/pubmed/25542002
http://dx.doi.org/10.1371/journal.pone.0116107

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