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ARAP3 Functions in Hematopoietic Stem Cells
ARAP3 is a GTPase-activating protein (GAP) that inactivates Arf6 and RhoA small GTPases. ARAP3 deficiency in mice causes a sprouting angiogenic defect resulting in embryonic lethality by E11. Mice with an ARAP3 R302,303A mutation (Arap3(KI/KI)) that prevents activation by phosphoinositide-3-kinase (...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277471/ https://www.ncbi.nlm.nih.gov/pubmed/25542002 http://dx.doi.org/10.1371/journal.pone.0116107 |