Design, Synthesis and Cytotoxicity Evaluationof New 1,2-diaryl-4, 5, 6, 7-Tetrahydro-1H-benzo[d] Imidazolesas Tubulin Inhibitors

A new series of 1,2-diaryl-4,5,6,7-tetrahydro-1H-benzo[d]imidazoles, possessing trimethoxyphenyl pharmacophore, were synthesized to evaluate their biological activities as tubulin inhibitors. Cytotoxic activity of the synthesized compounds 7a-f was assessed against several human cancer cell lines, i...

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Detalles Bibliográficos
Autores principales: Amirmostofian, Marzieh, Kobarfard, Farzad, Reihanfard, Hamed, Mashayekhi, Vida, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277619/
https://www.ncbi.nlm.nih.gov/pubmed/25561912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277619/
https://www.ncbi.nlm.nih.gov/pubmed/25561912

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