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Synthesis and Preliminary Evaluation of a New (99m)Tc Labeled Substance P Analogue as a Potential Tumor Imaging Agent
Neurokinin 1 receptors (NK(1)R) are overexpressed on several types of important human cancer cells. Substance P (SP) is the most specific endogenous ligand known for NK(1)Rs. Accordingly,a new SP analogue was synthesized and evaluated for detection of NK(1)R positive tumors.[6-hydrazinopyridine-3-ca...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shaheed Beheshti University of Medical Sciences
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277623/ https://www.ncbi.nlm.nih.gov/pubmed/25561916 |