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Effect of Cysteamine on Cell Growth and IgG(4) Production in Recombinant Sp2.0 Cells

The manipulation of redox potential in secretory pathway by thiol reducing agents can be a strategy to improve the production levels of disulfide-bonded proteins including recombinant antibodies. Here we have studied the influence of cysteamine on viability and the production level of IgG(4) in Sp2....

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Detalles Bibliográficos
Autores principales: Jahandar, Hoda, Vaziri, Behrouz, Nematollahi, Leila, Afsharirad, Tayebeh, Mirabzadeh, Esmat, Torkashvand, Fatemeh, Khalaj, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277631/
https://www.ncbi.nlm.nih.gov/pubmed/25561924