Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts

[Image: see text] Highly enantioselective selenocyclization reactions are promoted by the combination of a new chiral squaramide catalyst, a mineral acid, and an achiral Lewis base. Mechanistic studies reveal that the enantioselectivity originates from the dynamic kinetic resolution of seleniranium...

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Autores principales: Zhang, Hu, Lin, Song, Jacobsen, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277748/
https://www.ncbi.nlm.nih.gov/pubmed/25380129
http://dx.doi.org/10.1021/ja510113s
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author Zhang, Hu
Lin, Song
Jacobsen, Eric N.
author_facet Zhang, Hu
Lin, Song
Jacobsen, Eric N.
author_sort Zhang, Hu
collection PubMed
description [Image: see text] Highly enantioselective selenocyclization reactions are promoted by the combination of a new chiral squaramide catalyst, a mineral acid, and an achiral Lewis base. Mechanistic studies reveal that the enantioselectivity originates from the dynamic kinetic resolution of seleniranium ions through anion-binding catalysis.
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spelling pubmed-42777482015-11-07 Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts Zhang, Hu Lin, Song Jacobsen, Eric N. J Am Chem Soc [Image: see text] Highly enantioselective selenocyclization reactions are promoted by the combination of a new chiral squaramide catalyst, a mineral acid, and an achiral Lewis base. Mechanistic studies reveal that the enantioselectivity originates from the dynamic kinetic resolution of seleniranium ions through anion-binding catalysis. American Chemical Society 2014-11-07 2014-11-26 /pmc/articles/PMC4277748/ /pubmed/25380129 http://dx.doi.org/10.1021/ja510113s Text en Copyright © 2014 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Zhang, Hu
Lin, Song
Jacobsen, Eric N.
Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts
title Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts
title_full Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts
title_fullStr Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts
title_full_unstemmed Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts
title_short Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts
title_sort enantioselective selenocyclization via dynamic kinetic resolution of seleniranium ions by hydrogen-bond donor catalysts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277748/
https://www.ncbi.nlm.nih.gov/pubmed/25380129
http://dx.doi.org/10.1021/ja510113s
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AT linsong enantioselectiveselenocyclizationviadynamickineticresolutionofseleniraniumionsbyhydrogenbonddonorcatalysts
AT jacobsenericn enantioselectiveselenocyclizationviadynamickineticresolutionofseleniraniumionsbyhydrogenbonddonorcatalysts

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