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Nanopores Discriminate among Five C5-Cytosine Variants in DNA
[Image: see text] Individual DNA molecules can be read at single nucleotide precision using nanopores coupled to processive enzymes. Discrimination among the four canonical bases has been achieved, as has discrimination among cytosine, 5-methylcytosine (mC), and 5-hydroxymethylcytosine (hmC). Two ad...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277752/ https://www.ncbi.nlm.nih.gov/pubmed/25347819 http://dx.doi.org/10.1021/ja508527b |