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Nickel-Catalyzed Negishi Arylations of Propargylic Bromides: A Mechanistic Investigation

[Image: see text] Although nickel-catalyzed stereoconvergent couplings of racemic alkyl electrophiles are emerging as a powerful tool in organic chemistry, to date there have been no systematic mechanistic studies of such processes. Herein, we examine the pathway for enantioselective Negishi arylati...

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Detalles Bibliográficos
Autores principales: Schley, Nathan D., Fu, Gregory C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277758/
https://www.ncbi.nlm.nih.gov/pubmed/25402209
http://dx.doi.org/10.1021/ja508718m