Systematic Transfer of Prokaryotic Sensors and Circuits to Mammalian Cells

[Image: see text] Prokaryotic regulatory proteins respond to diverse signals and represent a rich resource for building synthetic sensors and circuits. The TetR family contains >10(5) members that use a simple mechanism to respond to stimuli and bind distinct DNA operators. We present a platform...

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Detalles Bibliográficos
Autores principales: Stanton, Brynne C., Siciliano, Velia, Ghodasara, Amar, Wroblewska, Liliana, Clancy, Kevin, Trefzer, Axel C., Chesnut, Jonathan D., Weiss, Ron, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277766/
https://www.ncbi.nlm.nih.gov/pubmed/25360681
http://dx.doi.org/10.1021/sb5002856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277766/
https://www.ncbi.nlm.nih.gov/pubmed/25360681
http://dx.doi.org/10.1021/sb5002856

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