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Systematic Transfer of Prokaryotic Sensors and Circuits to Mammalian Cells
[Image: see text] Prokaryotic regulatory proteins respond to diverse signals and represent a rich resource for building synthetic sensors and circuits. The TetR family contains >10(5) members that use a simple mechanism to respond to stimuli and bind distinct DNA operators. We present a platform...
Autores principales: | Stanton, Brynne C., Siciliano, Velia, Ghodasara, Amar, Wroblewska, Liliana, Clancy, Kevin, Trefzer, Axel C., Chesnut, Jonathan D., Weiss, Ron, Voigt, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277766/ https://www.ncbi.nlm.nih.gov/pubmed/25360681 http://dx.doi.org/10.1021/sb5002856 |
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