Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways

The aryl hydrocarbon receptor (AhR) is a heterodimeric transcriptional regulator with pleiotropic functions in xenobiotic metabolism and detoxification, vascular development and cancer. Herein, we report a previously undescribed role for the AhR signalling pathway in the pathogenesis of the wet, neo...

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Detalles Bibliográficos
Autores principales: Choudhary, Mayur, Kazmin, Dmitri, Hu, Peng, Thomas, Russell S, McDonnell, Donald P, Malek, Goldis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277859/
https://www.ncbi.nlm.nih.gov/pubmed/25186463
http://dx.doi.org/10.1002/path.4433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277859/
https://www.ncbi.nlm.nih.gov/pubmed/25186463
http://dx.doi.org/10.1002/path.4433

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