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Modulation of CFTR gating by permeant ions

Cystic fibrosis transmembrane conductance regulator (CFTR) is unique among ion channels in that after its phosphorylation by protein kinase A (PKA), its ATP-dependent gating violates microscopic reversibility caused by the intimate involvement of ATP hydrolysis in controlling channel closure. Recent...

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Detalles Bibliográficos
Autores principales: Yeh, Han-I, Yeh, Jiunn-Tyng, Hwang, Tzyh-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278182/
https://www.ncbi.nlm.nih.gov/pubmed/25512598
http://dx.doi.org/10.1085/jgp.201411272