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Structural model of the open–closed–inactivated cycle of prokaryotic voltage-gated sodium channels

In excitable cells, the initiation of the action potential results from the opening of voltage-gated sodium channels. These channels undergo a series of conformational changes between open, closed, and inactivated states. Many models have been proposed for the structural transitions that result in t...

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Detalles Bibliográficos
Autores principales: Bagnéris, Claire, Naylor, Claire E., McCusker, Emily C., Wallace, B.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278185/
https://www.ncbi.nlm.nih.gov/pubmed/25512599
http://dx.doi.org/10.1085/jgp.201411242