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Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis

EGFR is one of the key oncogenes subjected to targeted therapy for several cancers, as it is known to be amplified and/or mutated in up to 40% of malignant gliomas. EFEMP1, a fibulin-like extracellular protein, exerts both tumor suppressive and oncogenic effects in various cancers and glioma cell mo...

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Detalles Bibliográficos
Autores principales: Hu, Yuanjie, Gao, Hengjun, Vo, Christopher, Ke, Chao, Pan, Francine, Yu, Liping, Siegel, Eric, Hess, Kenneth R., Linskey, Mark E., Zhou, Yi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278290/
https://www.ncbi.nlm.nih.gov/pubmed/25594013