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Epidermal growth factor receptor (EGFR) mutations are exceptionally rare in thyroid transcription factor (TTF-1)-negative adenocarcinomas of the lung

INTRODUCTION: Approximately 70% of lung adenocarcinomas express TTF-1. EGFR mutations are present in 13-15% of Western adenocarcinoma patients. This paper investigates TTF1 as a negative predictor of mutant EGFR in lung adenocarcinomas. RESULTS: In the pilot cohort (N = 301) two of 224 specimens pos...

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Detalles Bibliográficos
Autores principales: Somaiah, Neeta, Fidler, Mary Jo, Garrett-Mayer, Elizabeth, Wahlquist, Amy, Shirai, Keisuke, Buckingham, Lela, Hensing, Thomas, Bonomi, Philip, Simon, George R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278331/
https://www.ncbi.nlm.nih.gov/pubmed/25594059