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Targeting the oncogene B lymphoma deregulator IgH 3′ regulatory region does not impede the in vivo inflammatory response in mice

The IgH 3′ regulatory region (3′RR), encompassing the four transcriptional enhancers hs3a-hs1,2-hs3b-hs4, is a potent lymphoma oncogene deregulator but its role in B cell-mediated inflammatory responses is unknown. We investigated the 3′RR involvement in the in vivo pristane-induced inflammatory res...

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Detalles Bibliográficos
Autores principales: Saad, Faten, Saintamand, Alexis, Rouaud, Pauline, Denizot, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278336/
https://www.ncbi.nlm.nih.gov/pubmed/25594069