Systematic evaluation of connectivity map for disease indications

BACKGROUND: Connectivity map data and associated methodologies have become a valuable tool in understanding drug mechanism of action (MOA) and discovering new indications for drugs. One of the key ideas of connectivity map (CMAP) is to measure the connectivity between disease gene expression signatu...

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Detalles Bibliográficos
Autores principales: Cheng, Jie, Yang, Lun, Kumar, Vinod, Agarwal, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278345/
https://www.ncbi.nlm.nih.gov/pubmed/25606058
http://dx.doi.org/10.1186/s13073-014-0095-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278345/
https://www.ncbi.nlm.nih.gov/pubmed/25606058
http://dx.doi.org/10.1186/s13073-014-0095-1

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