ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS Toxin Regulates Inflammasome Activity

The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates the severity of inflammation associated with a wide spectrum of inflammatory dise...

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Detalles Bibliográficos
Autores principales: Bose, Santanu, Segovia, Jesus A., Somarajan, Sudha R., Chang, Te-Hung, Kannan, T. R., Baseman, Joel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278538/
https://www.ncbi.nlm.nih.gov/pubmed/25538194
http://dx.doi.org/10.1128/mBio.02186-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278538/
https://www.ncbi.nlm.nih.gov/pubmed/25538194
http://dx.doi.org/10.1128/mBio.02186-14

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