Disulfide-Mediated Stabilization of the IκB Kinase Binding Domain of NF-κB Essential Modulator (NEMO)

[Image: see text] Human NEMO (NF-κB essential modulator) is a 419 residue scaffolding protein that, together with catalytic subunits IKKα and IKKβ, forms the IκB kinase (IKK) complex, a key regulator of NF-κB pathway signaling. NEMO is an elongated homodimer comprising mostly α-helix. It has been sh...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Yeo, Alan T., Ballarano, Carmine, Weber, Urs, Allen, Karen N., Gilmore, Thomas D., Whitty, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278678/
https://www.ncbi.nlm.nih.gov/pubmed/25400026
http://dx.doi.org/10.1021/bi500920n

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278678/
https://www.ncbi.nlm.nih.gov/pubmed/25400026
http://dx.doi.org/10.1021/bi500920n

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