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Citrate Synthase Expression Affects Tumor Phenotype and Drug Resistance in Human Ovarian Carcinoma

Citrate synthase (CS), one of the key enzymes in the tricarboxylic acid (TCA) cycle, catalyzes the reaction between oxaloacetic acid and acetyl coenzyme A to generate citrate. Increased CS has been observed in pancreatic cancer. In this study, we found higher CS expression in malignant ovarian tumor...

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Detalles Bibliográficos
Autores principales: Chen, Lilan, Liu, Ting, Zhou, Jinhua, Wang, Yunfei, Wang, Xinran, Di, Wen, Zhang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278743/
https://www.ncbi.nlm.nih.gov/pubmed/25545012
http://dx.doi.org/10.1371/journal.pone.0115708