The Vitamin D Receptor Inhibits the Respiratory Chain, Contributing to the Metabolic Switch that Is Essential for Cancer Cell Proliferation

We recently described the mitochondrial localization and import of the vitamin D receptor (VDR) in actively proliferating HaCaT cells for the first time, but its role in the organelle remains unknown. Many metabolic intermediates that support cell growth are provided by the mitochondria; consequentl...

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Detalles Bibliográficos
Autores principales: Consiglio, Marco, Destefanis, Michele, Morena, Deborah, Foglizzo, Valentina, Forneris, Mattia, Pescarmona, Gianpiero, Silvagno, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278832/
https://www.ncbi.nlm.nih.gov/pubmed/25546457
http://dx.doi.org/10.1371/journal.pone.0115816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278832/
https://www.ncbi.nlm.nih.gov/pubmed/25546457
http://dx.doi.org/10.1371/journal.pone.0115816

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