Cargando…
The Vitamin D Receptor Inhibits the Respiratory Chain, Contributing to the Metabolic Switch that Is Essential for Cancer Cell Proliferation
We recently described the mitochondrial localization and import of the vitamin D receptor (VDR) in actively proliferating HaCaT cells for the first time, but its role in the organelle remains unknown. Many metabolic intermediates that support cell growth are provided by the mitochondria; consequentl...
Autores principales: | Consiglio, Marco, Destefanis, Michele, Morena, Deborah, Foglizzo, Valentina, Forneris, Mattia, Pescarmona, Gianpiero, Silvagno, Francesca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278832/ https://www.ncbi.nlm.nih.gov/pubmed/25546457 http://dx.doi.org/10.1371/journal.pone.0115816 |
Ejemplares similares
-
Mitochondrial Translocation of Vitamin D Receptor Is Mediated by the Permeability Transition Pore in Human Keratinocyte Cell Line
por: Silvagno, Francesca, et al.
Publicado: (2013) -
Mitochondrial Localization of Vitamin D Receptor in Human Platelets and Differentiated Megakaryocytes
por: Silvagno, Francesca, et al.
Publicado: (2010) -
The analysis of glutamate and glutamine frequencies in human proteins as marker of tissue oxygenation
por: Vernone, Annamaria, et al.
Publicado: (2019) -
How the Competition for Cysteine May Promote Infection of SARS-CoV-2 by Triggering Oxidative Stress
por: Vernone, Annamaria, et al.
Publicado: (2023) -
The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19
por: Silvagno, Francesca, et al.
Publicado: (2020)