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A Mathematical Model of Bimodal Epigenetic Control of miR-193a in Ovarian Cancer Stem Cells

Accumulating data indicate that cancer stem cells contribute to tumor chemoresistance and their persistence alters clinical outcome. Our previous study has shown that ovarian cancer may be initiated by ovarian cancer initiating cells (OCIC) characterized by surface antigen CD44 and c-KIT (CD117). It...

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Detalles Bibliográficos
Autores principales: Cheng, Frank H. C., Aguda, Baltazar D., Tsai, Je-Chiang, Kochańczyk, Marek, Lin, Jora M. J., Chen, Gary C. W., Lai, Hung-Cheng, Nephew, Kenneth P., Hwang, Tzy-Wei, Chan, Michael W. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278842/
https://www.ncbi.nlm.nih.gov/pubmed/25545504
http://dx.doi.org/10.1371/journal.pone.0116050