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A Mathematical Model of Bimodal Epigenetic Control of miR-193a in Ovarian Cancer Stem Cells
Accumulating data indicate that cancer stem cells contribute to tumor chemoresistance and their persistence alters clinical outcome. Our previous study has shown that ovarian cancer may be initiated by ovarian cancer initiating cells (OCIC) characterized by surface antigen CD44 and c-KIT (CD117). It...
Autores principales: | Cheng, Frank H. C., Aguda, Baltazar D., Tsai, Je-Chiang, Kochańczyk, Marek, Lin, Jora M. J., Chen, Gary C. W., Lai, Hung-Cheng, Nephew, Kenneth P., Hwang, Tzy-Wei, Chan, Michael W. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278842/ https://www.ncbi.nlm.nih.gov/pubmed/25545504 http://dx.doi.org/10.1371/journal.pone.0116050 |
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