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iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice

iRhom1 and iRhom2 are inactive homologues of rhomboid intramembrane serine proteases lacking essential catalytic residues, which are necessary for the maturation of TNFα-converting enzyme (TACE). In addition, iRhoms regulate epidermal growth factor family secretion. The functional significance of iR...

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Detalles Bibliográficos
Autores principales: Leilei, Yang, Bing, Liu, Yang, Li, Shaoxia, Wang, Yuan, Xu, Dongping, Wang, Huahu, Ye, Shichen, Shang, Guangzhou, Zhang, Ruiyun, Peng, Lin, Zeng, Wenlong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278852/
https://www.ncbi.nlm.nih.gov/pubmed/25546423
http://dx.doi.org/10.1371/journal.pone.0115114