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iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice
iRhom1 and iRhom2 are inactive homologues of rhomboid intramembrane serine proteases lacking essential catalytic residues, which are necessary for the maturation of TNFα-converting enzyme (TACE). In addition, iRhoms regulate epidermal growth factor family secretion. The functional significance of iR...
Autores principales: | Leilei, Yang, Bing, Liu, Yang, Li, Shaoxia, Wang, Yuan, Xu, Dongping, Wang, Huahu, Ye, Shichen, Shang, Guangzhou, Zhang, Ruiyun, Peng, Lin, Zeng, Wenlong, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278852/ https://www.ncbi.nlm.nih.gov/pubmed/25546423 http://dx.doi.org/10.1371/journal.pone.0115114 |
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