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The Ubiquitin E3 Ligase NOSIP Modulates Protein Phosphatase 2A Activity in Craniofacial Development

Holoprosencephaly is a common developmental disorder in humans characterised by incomplete brain hemisphere separation and midface anomalies. The etiology of holoprosencephaly is heterogeneous with environmental and genetic causes, but for a majority of holoprosencephaly cases the genes associated w...

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Detalles Bibliográficos
Autores principales: Hoffmeister, Meike, Prelle, Carola, Küchler, Philipp, Kovacevic, Igor, Moser, Markus, Müller-Esterl, Werner, Oess, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278855/
https://www.ncbi.nlm.nih.gov/pubmed/25546391
http://dx.doi.org/10.1371/journal.pone.0116150