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Combination Analysis in Genetic Polymorphisms of Drug-Metabolizing Enzymes CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in the Japanese Population

The Cytochrome P450 is the major enzyme involved in drug metabolism. CYP enzymes are responsible for the metabolism of most clinically used drugs. Individual variability in CYP activity is one important factor that contributes to drug therapy failure. We have developed a new straightforward TaqMan P...

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Detalles Bibliográficos
Autores principales: Ota, Tomoko, Kamada, Yuka, Hayashida, Mariko, Iwao-Koizumi, Kyoko, Murata, Shigenori, Kinoshita, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278879/
https://www.ncbi.nlm.nih.gov/pubmed/25552922
http://dx.doi.org/10.7150/ijms.10263