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Combination Analysis in Genetic Polymorphisms of Drug-Metabolizing Enzymes CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in the Japanese Population
The Cytochrome P450 is the major enzyme involved in drug metabolism. CYP enzymes are responsible for the metabolism of most clinically used drugs. Individual variability in CYP activity is one important factor that contributes to drug therapy failure. We have developed a new straightforward TaqMan P...
Autores principales: | Ota, Tomoko, Kamada, Yuka, Hayashida, Mariko, Iwao-Koizumi, Kyoko, Murata, Shigenori, Kinoshita, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278879/ https://www.ncbi.nlm.nih.gov/pubmed/25552922 http://dx.doi.org/10.7150/ijms.10263 |
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