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Clinical Significance of a Point Mutation in DNA Polymerase Beta (POLB) Gene in Gastric Cancer

Gastric cancer (GC) is a major cause of global cancer mortality. Genetic variations in DNA repair genes can modulate DNA repair capability and, consequently, have been associated with risk of developing cancer. We have previously identified a T to C point mutation at nucleotide 889 (T889C) in DNA po...

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Detalles Bibliográficos
Autores principales: Tan, Xiaohui, Wang, Hongyi, Luo, Guangbin, Ren, Shuyang, Li, Wenmei, Cui, Jiantao, Gill, Harindarpal S., Fu, Sidney W., Lu, Youyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279090/
https://www.ncbi.nlm.nih.gov/pubmed/25561897
http://dx.doi.org/10.7150/ijbs.10692