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Ubiquitination of ECSIT is crucial for the activation of p65/p50 NF-κBs in Toll-like receptor 4 signaling

Recent evidence shows that evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) interacts with tumor necrosis factor receptor–associated factor 6 (TRAF6), is ubiquitinated, and contributes to bactericidal activity during Toll-like receptor (TLR) signaling. Here we report a new re...

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Detalles Bibliográficos
Autores principales: Mi Wi, Sae, Park, Jeongho, Shim, Jae-Hyuck, Chun, Eunyoung, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279226/
https://www.ncbi.nlm.nih.gov/pubmed/25355951
http://dx.doi.org/10.1091/mbc.E14-08-1277