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WAVE binds Ena/VASP for enhanced Arp2/3 complex–based actin assembly
The WAVE complex is the main activator of the Arp2/3 complex for actin filament nucleation and assembly in the lamellipodia of moving cells. Other important players in lamellipodial protrusion are Ena/VASP proteins, which enhance actin filament elongation. Here we examine the molecular coordination...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279229/ https://www.ncbi.nlm.nih.gov/pubmed/25355952 http://dx.doi.org/10.1091/mbc.E14-07-1200 |