Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1

The inhibitor-of-apoptosis family member survivin has been reported to inhibit apoptosis and regulate mitosis and cytokinesis. In multiple myeloma, survivin has been described to be involved in downstream sequelae of various therapeutic agents. We assessed 1093 samples from previously untreated pati...

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Detalles Bibliográficos
Autores principales: Wagner, Verena, Hose, Dirk, Seckinger, Anja, Weiz, Ludmila, Meißner, Tobias, Rème, Thiery, Breitkreutz, Iris, Podar, Klaus, Ho, Anthony D., Goldschmidt, Hartmut, Krämer, Alwin, Klein, Bernard, Raab, Marc S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279369/
https://www.ncbi.nlm.nih.gov/pubmed/25296978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279369/
https://www.ncbi.nlm.nih.gov/pubmed/25296978

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