Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation

Radiation therapy is a staple treatment for pancreatic cancer. However, owing to the intrinsic radioresistance of pancreatic cancer cells, radiation therapy often fails to increase survival of pancreatic cancer patients. Radiation impedes cancer cells by inducing DNA damage, which can activate cell...

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Detalles Bibliográficos
Autores principales: Yan, Ying, Hein, Ashley L., Etekpo, Asserewou, Burchett, Katrina M., Lin, Chi, Enke, Charles A., Batra, Surinder K., Cowan, Kenneth H., Ouellette, Michel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279370/
https://www.ncbi.nlm.nih.gov/pubmed/25344910
http://dx.doi.org/10.18632/oncotarget.2500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279370/
https://www.ncbi.nlm.nih.gov/pubmed/25344910
http://dx.doi.org/10.18632/oncotarget.2500

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