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Notch signaling drives multiple myeloma induced osteoclastogenesis

Multiple myeloma (MM) is closely associated with bone destruction. Once migrated to the bone marrow, MM cells unbalance bone formation and resorption via the recruitment and maturation of osteoclast precursors. The Notch pathway plays a key role in different types of cancer and drives several biolog...

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Detalles Bibliográficos
Autores principales: Colombo, Michela, Thümmler, Katja, Mirandola, Leonardo, Garavelli, Silvia, Todoerti, Katia, Apicella, Luana, Lazzari, Elisa, Lancellotti, Marialuigia, Platonova, Natalia, Akbar, Moeed, Chiriva-Internati, Maurizio, Soutar, Richard, Neri, Antonino, Goodyear, Carl S., Chiaramonte, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279381/
https://www.ncbi.nlm.nih.gov/pubmed/25257302