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Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells

Thymidine phosphorylase (TP) promotes angiogenesis and metastasis, and confers resistance to anticancer agents in some cancer cell types. We previously reported that TP stimulates the expression of interleukin (IL)-8 in human KB cancer cells by an unknown mechanism. A mutation in the nuclear factor...

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Detalles Bibliográficos
Autores principales: Tabata, Sho, Ikeda, Ryuji, Yamamoto, Masatatsu, Shimaoka, Shunji, Mukaida, Naofumi, Takeda, Yasuo, Yamada, Katsushi, Soga, Tomoyoshi, Furukawa, Tatsuhiko, Akiyama, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279387/
https://www.ncbi.nlm.nih.gov/pubmed/25350954