De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells

Elevated expression of heat shock protein 5 (HSPA5) promotes drug resistance and metastasis and is a marker of poor prognosis in breast cancer patients. Adenovirus type 5 E1A gene therapy has demonstrated antitumor efficacy but the mechanisms of metastasis-inhibition are unclear. Here, we report tha...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Wen, Chen, Hsin-An, Tseng, Chi-Feng, Hong, Chih-Chen, Ma, Jui-Ti, Hung, Mien-Chie, Wu, Chih-Hsiung, Huang, Ming-Te, Su, Jen-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279393/
https://www.ncbi.nlm.nih.gov/pubmed/25301734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279393/
https://www.ncbi.nlm.nih.gov/pubmed/25301734

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