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De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells
Elevated expression of heat shock protein 5 (HSPA5) promotes drug resistance and metastasis and is a marker of poor prognosis in breast cancer patients. Adenovirus type 5 E1A gene therapy has demonstrated antitumor efficacy but the mechanisms of metastasis-inhibition are unclear. Here, we report tha...
Autores principales: | Chang, Yi-Wen, Chen, Hsin-An, Tseng, Chi-Feng, Hong, Chih-Chen, Ma, Jui-Ti, Hung, Mien-Chie, Wu, Chih-Hsiung, Huang, Ming-Te, Su, Jen-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279393/ https://www.ncbi.nlm.nih.gov/pubmed/25301734 |
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