An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities

The Ral (Ras-like) GTP-binding proteins (RalA and RalB), as effectors of the proto-oncogene Natural killer (NK) cells are an important component of the anti-tumor response. Tumor recognition by NK cells was found to be partly triggered by molecules termed natural cytotoxic receptors (NCRs). Adoptive...

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Detalles Bibliográficos
Autores principales: Tal, Yair, Yaakobi, Shlomo, Horovitz-Fried, Miryam, Safyon, Einav, Rosental, Benyamin, Porgador, Angel, Cohen, Cyrille J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279421/
https://www.ncbi.nlm.nih.gov/pubmed/25431955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279421/
https://www.ncbi.nlm.nih.gov/pubmed/25431955

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