Development of a monoclonal antibody specific to the endonuclease domain of the human LINE-1 ORF2 protein

BACKGROUND: LINE-1 (L1) retrotransposons are common occupants of mammalian genomes representing about a fifth of the genetic content. Ongoing L1 retrotransposition in the germ line and somatic tissues has contributed to structural genomic variations and disease-causing mutations in the human genome....

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Detalles Bibliográficos
Autores principales: Sokolowski, Mark, DeFreece, Cecily B, Servant, Geraldine, Kines, Kristine J, deHaro, Dawn L, Belancio, Victoria P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279459/
https://www.ncbi.nlm.nih.gov/pubmed/25606060
http://dx.doi.org/10.1186/s13100-014-0029-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279459/
https://www.ncbi.nlm.nih.gov/pubmed/25606060
http://dx.doi.org/10.1186/s13100-014-0029-x

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