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Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus

BACKGROUND: Latrunculin A microperfusion of the hippocampus induces acute epileptic seizures and long-term biochemical changes leading to spontaneous seizures. This study tested the effect of eslicarbazepine acetate (ESL), a novel antiepileptic drug, on latrunculin A-induced acute and chronic seizur...

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Detalles Bibliográficos
Autores principales: Sierra-Paredes, Germán, Loureiro, Ana I, Wright, Lyndon C, Sierra-Marcuño, Germán, Soares-da-Silva, Patrício
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279694/
https://www.ncbi.nlm.nih.gov/pubmed/25526768
http://dx.doi.org/10.1186/s12868-014-0134-2