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Succinate dehydrogenase subunit B inhibits the AMPK-HIF-1α pathway in human ovarian cancer in vitro

BACKGROUND: Ovarian carcinoma is one of the most common gynecological cancers with high mortality rates. Numerous evidences demonstrate that cancer cells undergo metabolic abnormality during tumorigenesis in tumor microenvironment and further facilitate tumor progression. Succinate dehydrogenase (SD...

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Detalles Bibliográficos
Autores principales: Chen, Lilan, Liu, Ting, Zhang, Shu, Zhou, Jinhua, Wang, Yunfei, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279696/
https://www.ncbi.nlm.nih.gov/pubmed/25491408
http://dx.doi.org/10.1186/s13048-014-0115-1